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Beilstein J. Org. Chem. 2010, 6, No. 21, doi:10.3762/bjoc.6.21
Graphical Abstract
Figure 1: Typical representatives of iminosugars.
Figure 2: N-Modified iminosugars 5–9 as potential pharmacological chaperones.
Figure 3: Structure of NOEV 10.
Scheme 1: Three-step-synthesis of partially protected 1-deoxy-D-galactonojirimycin derivative 12 from 10 via ...
Scheme 2: Synthesis of N-(6-aminohexyl)-1-deoxygalactonojirimycin (15) from 12 via 14.
Scheme 3: Synthesis of lipophilic 1-deoxy-D-galactonojirimycin derivatives 16–18 by chemoselective acylation ...
Scheme 4: Synthesis of compounds 19 as well as 20 from primary amine 15.
Scheme 5: Synthesis of compound 22.